Amoxicillin Trihydrate API is antibiotic used to treating various bacterial infections, including respiratory (pneumonia, bronchitis), ear, nose, throat, skin, and urinary tract infections, as well as conditions like streptococcal pharyngitis, Lyme disease, and certain STIs.
Key Properties:
- Chemical Name: (2S,5R,6R)-6-[(R)-(-)-2-Amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicycloheptane-2-carboxylic acid trihydrate,
- CAS Number: 61336-70-7
- Molecular Formula: C₁₆H₁₉N₃O₅S
- Molecular Weight: 419.45 g/mol
- Appearance: White or almost white crystalline powder. It is also sometimes described as a white to pale yellow or off-white solid.
- Solubility: Amoxicillin Trihydrate API is sparingly to slightly soluble in water, with solubility increasing significantly in dilute acids or alkaline solutions, but it’s practically insoluble in alcohol and organic solvents like ether/chloroform.
- Mechanism of Action: It is a semisynthetic penicillin which acts by inhibiting the bacterial cell wall synthesis. It is penicillate sensitive and is effective against gram positive organisms and gram-negative microorganisms but is inactive against beta-lactamase producing organisms.
- Bioavailability: Amoxicillin trihydrate, when administered orally as an active pharmaceutical ingredient (API) in immediate-release formulations up to a dose of 875 mg, has a high oral bioavailability ranging from approximately 74% to 92%.
- Half-life: The elimination half-life of amoxicillin trihydrate in humans is approximately 61.3 Minutes.
- Metabolism: Amoxicillin is metabolized to a limited extent in the body, with a significant portion (60-70%) excreted unchanged in the urine.
- Uses: Amoxicillin is used to treat bacterial infections in many different parts of the body (ear, lungs, nose, sinus, skin, urinary tract)
- Seller: –Amoxicillin Trihydrate API Available at Vimara Enterprises.
