Tadalafil

Tadalafil API is used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.

Key Properties:
  • Chemical Name: (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1′,2′:1,6]
    pyrido[3,4-b]indole-1,4-dione
  • CAS Number: 171596-29-5
  • Molecular Formula: C22H19N3O4
  • Molecular Weight: 389.404 g/mol
  • Appearance: Tadalafil API powder typically appears as a white crystalline or crystalline powder.
  • Solubility: Tadalafil API powder is practically insoluble in water, tadalafil API exhibits better solubility in organic solvents like DMSO and DMF
  • Mechanism of Action: Tadalafil API is works by preventing the breakdown of cGMP, leading to smooth muscle relaxation, vasodilation, and ultimately, an erection. This mechanism also has beneficial effects on the pulmonary vasculature.
  • Bioavailability: Tadalafil API has a bioavailability of approximately 40-80%.
  • Half-life: The half-life of Tadalafil API is approximately 17.5 hours.
  • Metabolism: Tadalafil API is mainly metabolized by CYP3A4 in the liver.
  • Uses: Tadalafil API Primarily used for the treatment of erectile dysfunction. 
  • SellerTadalafil API Available at Vimara Enterprises.