Acyclovir API is the core component of antiviral drugs used to treat infections from herpes viruses, including genital herpes, cold sores, shingles, and chickenpox
Key Properties:
- Chemical Name: 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one, also known as 9-[(2-Hydroxyethoxy)methyl]guanine
- CAS Number: 59277-89-3
- Molecular Formula: C₈H₁₁N₅O₃
- Molecular Weight: 225.2 g/mol
- Appearance: Acyclovir API typically appears as a white powder or white crystalline powder
- Solubility: Acyclovir API is slightly soluble in water but becomes more soluble in dilute acids/alkalis, DMSO, and as its sodium salt is readily soluble in water
- Mechanism of Action: Acyclovir is an antiviral active pharmaceutical ingredient (API) that works by inhibiting viral DNA replication through a specific, multi-step mechanism of action (MOA) that is selective for virus-infected cells.
- Bioavailability: Acyclovir API characterized by poor oral bioavailability, typically ranging from 10% to 20% in humans
- Half-life: Acyclovir’s (API) half-life is generally 2.5 to 3.5 hours in adults with normal kidney function
- Metabolism: Acyclovir API undergoes minimal metabolism in the human body and is primarily eliminated unchanged by the kidneys
- Uses: Acyclovir is used to treat shingles (herpes zoster), genital herpes, and chickenpox
- Seller: Acyclovir API Available at Vimara Enterprises.
