Diclofenac Potassium API used for
Key Properties:
- Chemical Name: Potassium 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid
- CAS Number: 15307-81-0
- Molecular Formula: C₁₄H₁₀Cl₂KNO₂
- Molecular Weight: 334.24 g/mol
- Appearance: White to slightly yellowish crystalline powder
- Solubility: Freely soluble in water; soluble in methanol; slightly soluble in ethanol
- Mechanism of Action: Diclofenac Potassium is a non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes (COX-1 and COX-2), resulting in reduced synthesis of prostaglandins responsible for inflammation, pain, and fever
- Bioavailability: Approximately 50–60% after oral administration due to first-pass metabolism
- Half-life: Approximately 1–2 hours
- Metabolism: Extensively metabolized in the liver mainly by CYP2C9 to hydroxylated metabolites; excreted via urine and bile
- Uses: Treatment of pain and inflammatory conditions, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute musculoskeletal pain, post-operative pain, dysmenorrhea, and migraine attacks
- Seller: Diclofenac Potassium API Available at Vimara Enterprises.
